TY - JOUR AU - Torisawa, Yu-suke PY - 2019 TI - Engineering bone marrow-on-a-chip JF - Microphysiological Systems; Vol 3 (March 2019): Microphysiological Systems Y2 - 2019 KW - N2 - Bone marrow is the permanent hematopoietic organ; the main function is to produce blood cells for the body through life. The microenvironment of bone marrow contains a complex set of cellular, chemical, and physical signals to maintain the hematopoietic system (1-3). The hematopoietic niche regulates hematopoietic stem cells (HSCs) to facilitate a balance between self-renewal and differentiation into progenitor cells that produce all types of blood cells. UR - https://mps.amegroups.org/article/view/5066